4 year PhD studentships
in cancer research
Applications are now open for Cancer Research UK funded
PhD studentships at the Paterson Institute for Cancer Research,
starting in Autumn 2012. A wide range of projects are on offer,
from those investigating the molecular and cellular basis of cancer,
to those focused on translational research and the development
of novel therapeutic approaches. Projects include:
• Applied Computational Biology and Bioinformatics – Crispin Miller:
The systems biology of cancer
• Cell Cycle – Karim Labib: How do eukaryotic cells unpack and copy
chromatin during chromosome replication?
• Cell Division – Iain Hagan: Addressing how cells get into mitosis; the
preparations for division in G2 phase
• Cell Regulation – Nic Jones: Stress signalling pathways in tumourigenesis
• Cell Signalling – Angeliki Malliri: Role of the Rac activator STEF (Tiam2)
in tumourigenesis
• Clinical and Experimental Pharmacology – Caroline Dive: Pre-clinical
models to measure cell population dynamics using PET imaging for
biomarker development
• DNA Damage and Response – Ivan Ahel: Poly(ADP-ribosyl)ation in
regulation of DNA repair
• Immunology – Peter Stern and Vaskar Saha: The role of 5T4 oncofoetal
molecules in modulating chemokine and Wnt response pathways in cancer
• Inositides – Nullin Divecha: Recruitment and regulation of phosphoinositide
kinases and their role in cancer development
• Molecular Oncology – Richard Marais: Transgenic models to study
gene-gene and gene-environment interactions in melanoma
• Signalling Networks in Cancer – John Brognard: Novel driver mutations
in cancer-associated tyrosine kinases in lung cancer
• Stem Cell Biology – Valerie Kouskoff: Molecular control of haematopoiesis
in health and disease
At the Paterson Institute, all our students benefi t from:
• World-class facilities, including next generation sequencing, microarrays,
mass-spectrometry, advanced imaging, histology, GCLP labs and fl ow cytometry.
• Core funding by Cancer Research UK, the largest independent cancer
research charity in the world.
• A generous stipend of £19,000 per year (tax free).
• Group leaders focused only on research and postgraduate training.
• Working alongside over 400 Postdoctoral Scientists, Clinical Fellows,
Scientifi c Offi cers, administrative and technical staff, postgraduate research
students and visiting fellows.
• Being at the heart of the Manchester Cancer Research Centre, a partnership
that brings together the expertise, vision and resources of its founding partners:
The University of Manchester, The Christie NHS Foundation Trust and Cancer
Research UK – all of which have formidable individual reputations in the fi elds
of cancer treatment and basic and clinical research.
• Cancer research in Manchester was ranked by the recent government Research
Assessment Exercise (RAE 2008) as the best in the UK.
We are committed to training the next generation of cancer research scientists,
helping launch careers in basic, translational and clinical cancer research.
Postgraduate students enjoy a supportive environment, a challenging project
and, together with tailored training in transferable and generic skills, will
develop as independent scientists with excellent career prospects.
CRUK PhDs within the Paterson are 4 years, international, and eligible to
students from within the UK, the EU and beyond. They come with a Cancer
Research UK stipend and full University tuition fees for the 4 years.
Informal enquiries should be addressed to Dr Crispin Miller, the Postgraduate Tutor
at: pgt@picr.man.ac.uk
The deadline for receipt of applications is 1st December 2011.
Applications received after this date will not be considered.
Interviews will be scheduled week commencing 30th January 2012.
To fi nd out more about our research, full details of the projects, plus application
forms and entry criteria, please visit our website.
www.paterson.man.ac.uk
12 | NewScientist | 22 October 2011 www.newscientistjobs.com/graduate
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